The breakthrough needed to overcome a critically important deficiency in infection control. A new, fast, convenient and safe method for  decontamination of medical instruments, surfaces, and tissues by  simple immersion in an aqueous solution. BRIO HOCL PrP Formula TM is a proven anti-prion reagent to combat misfolded infectious proteins, and the recommended proprietary disinfection solution to combat all misfolded infectious proteins. This patent pending product is currently available  for research use.
 A BRIOTECH BREAKTHROUGH
BRIO    HOCL    PrP    Formula TM       is   a   certified   pure   formulation     of      hypochlorous      acid      that contains     no     buffers.     It     has been     laboratory     tested     and proven   to   be   the   world’s   first safe    method    to    eliminate    all detectable   seeding   activity   of misfolded   infectious   proteins, and      is      safe      for      skin      and mucosal contact.
Dodge: Exclusive Distribution for Funeral Service From   its   founding   in   1893,   Dodge   has   consistently   developed   and   delivered   innovative products   that   serve   the   needs   of   the   funeral   industry.      Since   its   early   years   with   the establishment    of    schools    to    teach    the    science    of    embalming,    to    the    more    current introduction   of   formaldehyde-free   chemicals,   Dodge   has   led   the   way.   Today,   Dodge,              a   fourth   generation   family   business,   is   the   largest   provider   of   embalming   chemicals and     supplies     with     subsidiaries     and     distributors     located     throughout     the     world.               Briotech   Inc.   is   honored   to   partner   with   this   industry   leader   for   exclusive   distribution of BRIO   HOCL PrP Formula TM  into the funeral service industry.
BRIO    HOCL   PrP   Formula TM    is   available   for   the   funeral   industry   through   Dodge   in   the following countries: 
Please contact your Dodge Sales Representative at their customer service line at 800.443.6343 or email them at:  custserv@dodgeco.com 
ACTIVE INGREDIENTBRIO HOCL Pure HOCL™, 0.03%
USA CANADA MEXICO EL SALVADOR COLUMBIA JAMAICA VIRGIN ISLANDS SPAIN PORTUGAL ITALY
SWEDEN UK IRELAND HOLLAND FRANCE GERMANY CZECHOSLOVAKIA BELGIUM POLAND HUNGARY ROMANIA
RUSSIA JAPAN SINGAPORE PHILIPPINES CAMBODIA VIETNAM AUSTRALIA GHANA NIGERIA UGANDA
BRIOTECH, ITS LOGOS, LANGUAGE, AND IMAGES ARE TRADEMARKS AND/OR THE COPYRIGHT PROPERTY OF BRIOTECH, INC. AND/OR ITS AFFILIATES. © 2013-2018
BRIOTECH, ITS LOGOS, LANGUAGE, AND IMAGES ARE TRADEMARKS AND/OR THE COPYRIGHT PROPERTY OF BRIOTECH, INC. AND/OR ITS AFFILIATES. © 2013-2018
# P R O V E N P U R E
FDA FACILITY REG #3012261723 | EPA #93108
BR I O T E C H ,  I N C . Woodinville, WA 98072, USA b r i o t e c h u s a . c o m
September 29th, 2016 11:02 AM PDT
P R E S S  R E L E A S E
NIH   Scientists   and   collaborators   report   that   Briotech   Inc.’s   proprietary   HOC l    formulation rapidly    inactivates    resistant    infectious    proteins,    known    as    prions,    that    cause    Mad    Cow, Chronic   Wasting,   and   Creutzfeldt–Jakob   Disease,   and   are   now   implicated   in   Alzheimer’s   and other chronic brain diseases WOODINVILLE,   Wash.   (September   29,   2016)   Briotech   Inc.   today   announced   that   a   study published   in   the   current   issue   of   PLOS   Pathogens       proves   that   Briotech’s   unique   formulation of   pure   hypochlorous   acid   (HOC l )   inactivates   infectious   proteins,   known   as   prions,   that   cause chronic brain diseases in humans and animals.  Investigators   at   the   US   National   Institute   of   Allergy   and   Infectious   Diseases   (NIAID)   Rocky Mountain     Laboratories,     made     the     discovery     in     collaboration     with     researchers     at     the University    of    Washington    (UW)    Bothell,    UW    Seattle,    the    University    of    Verona    (Italy),                and    Briotech    Inc.    Their        findings    demonstrate    that    Briotech’s    patent-pending    solution (BrioHOC l TM )   quickly   and   safely   destroys   prions,   the   most   resistant   infectious   agents   known to medical science. HOC l     is    made    naturally    in    human    white    blood    cells    as    a    key    part    of    the    body’s    internal defense    system.    It    works    as    the    first    line    of    defense    at    wound    sites    to    fight    infection. Briotech’s    proprietary    Electro-Chemical    Activation    (ECA)    technology    enables    large-scale production    of    this    powerful    natural    compound    for    use    in    consumer    and    professional healthcare settings. “We’ve   been   able   to   synthesize   the   same   pure   substance   that   the   body   creates   to   defend itself   as   a   new   weapon   in   the   fight   against   infectious   disease,   and   it’s   a   game   changer   for human    health,”    said    Dan    Terry,    founder,    and    CEO    of    Briotech.    “With    broad    adoption    of BrioHOC l TM ,   we   can   help   stop   the   spread   of   many   infectious   diseases,   even   those   caused   by the   most   highly   resistant   agents   ever   discovered prions and   use   the   product   to   save   lives and   improve   the   health   of   entire   communities   around   the   world.   We’re   excited   to   have   this research   published   in   PLOS   Pathogens ,   and   look   forward   to   our   continued   collaboration   with the   NIH   on   the   effects   of   BrioHOC l TM    on   emerging   infectious   pathogens   that   threaten   global health and safety.” DESTROYING PRIONS Prions   are   abnormal,   misfolded   body   proteins   that   go   out   of   control   and   begin   to   multiply themselves,    spreading    throughout    the    body    and    invading    the    brain.    Prions    are    most commonly   transmitted   orally,   but   can   also   contaminate   medical   and   surgical   instruments, transplanted   tissues,   and   equipment   used   in   food   processing.   A   new,   fast,   convenient   and safe   method   for   decontamination   of   medical   instruments,   surfaces,   and   tissues by   simple immersion   in   an   aqueous   solution   of   Briotech’s   pure   BrioHOC l TM can   overcome   a   critically important    deficiency    in    infection    control    today.    It    can    mitigate    risks,    and    limit    liabilities related to healthcare procedures and hospital acquired diseases. Prion   diseases   are   most   widely   known   as   the   cause   of   Mad   Cow   Disease   (BSE).   Prions   also cause   Creutzfeldt-Jakob   Disease   (CJD)   in   humans,   a   fatal   dementia   with   a   long   incubation period.   Recently,   research   has   shown   that   most   other   chronic   degenerative   diseases   that lead    to    dementia,    including    Alzheimer’s,    result    from    prions.    Currently    untreatable,    and inevitably    fatal,    controversy    swirls    around    their    possible    transmissibility    as    referenced    in Nature  ( nature.com/news/the-red-hot-debate-about-transmissible-alzheimers ) Prions   are   uniquely   resistant   to   the   disinfection   and   sterilization   procedures   in   common   use in   healthcare   practice   today.   Extreme   measures   are   needed.   Current   prion   decontamination protocols   are   hazardous   to   people,   damaging   to   instruments   and   surfaces,   and   therefore impractical   for   transmission   control.   “Briotech   has   developed   an   enabling   technology,   one that   offers   for   the   first   time   a   practical   and   safe   way   of   destroying   infectious   prions,   the disease   agents   at   the   very   top   of   the   food   chain   when   it   comes   to   resistance   to   disinfection measures,”   said   Jeff   Williams,   PhD,   BVSc,   Chief   Scientific   Officer   at   Briotech.   “We   believe we’ve   just   exposed   the   tip   of   the   iceberg   when   it   comes   to   revealing   the   full   potential   of   the pure   HOC l   in   controlling   and   preventing   many   transmissible   diseases.   That’s   so   important today   when   rampant   antibiotic   resistance   is   challenging   established   approaches   to   infectious disease    management    all    over    the    world.    The    discovery    reported    in    PLOS    Pathogens     has opened   new   avenues   for   researchers   to   explore   in   understanding   the   relationship   between the   HOC l    made   in   the   brain,   its   possible   involvement   in   prion   inactivation   there,   and   the disease   processes   that   lead   to   dementia.   Understanding   those   processes   is   one   of   the   most urgent priorities facing biomedical science at this time.” HOW IT WORKS BrioHOC l TM      is     easy     to     handle,     safe     for     both     users     and     treated     surfaces     and     is environmentally   safe.   Pure   HOC l ,      used   in   the   PLOS   Pathogens    report,   is   reliably   stable   in   its formulation   and   powerfully   effective   against   a   wide   range   of   conventional   microbial   disease agents.   The   solution   can   be   applied   directly   to   skin   and   mucous   membranes,   hard   surfaces, instruments, or safely aerosolized to decontaminate entire rooms. Briotech    manufactures    BrioHOC l TM     in    fully-automated    production    platforms    inside    20’ shipping   containers,   enabling   production   and   distribution   of   a   consistent   and   pure   form   of HOC l  virtually anywhere in the world. ABOUT BRIOTECH INCORPORATED Based    in    Woodinville,    WA,    the    company    was    founded    in    2013    to    commercialize    the production   of   pure   HOC l ,   a   powerful,   safe,   naturally   occurring   substance,   effective   against the    whole    range    of    infectious    disease    pathogens    of    humans    and    animals,    and    to    make    it readily     available     throughout     the     world.     Briotech’s     introduction     of     transportable,     self- contained   manufacturing   systems   makes   high   volume   production   of   consistent   and   reliable HOC l     solutions    possible    for    the    first    time    ever.    Its    proprietary    electrolysis    technology creates   unique   formulations   of   stable   HOC l    for   a   wide   range   of   applications   in   consumer, medical,       agricultural       and       industrial       settings.       More       information       is       available       at briotechusa.com . ABOUT THE RESEARCH STUDY The   research   study   titled   “Inactivation   of   Prions   and   Amyloid   seeds   with   Hypochlorous   Acid” appears in the current issue of PLOS Pathogens  here: dx.plos.org/10.1371/journal.ppat.1005914 BrioHOC l TM       treatment   led   to      a   high   level   of   inactivation   after   short   exposure   times   for transmissible   prions   of   CJD,   BSE,   and   CWD,   but   also   for   self-replicating   proteins   found   in Alzheimer’s,    Parkinson’s    and    other    dementias.    Infectivity    of    BrioHOC l TM   treated    scrapie prions in mice was also highly significantly reduced.
B R I O    H O C L   P r P   F O R M U L A  TM
A BRIOTECH BREAKTHROUGH
BRIO    HOCL   PrP   Formula TM    is a    certified    pure    formulation of      hypochlorous      acid      that contains     no     buffers.     It     has been    laboratory    tested    and proven   to   be   the   world’s   first safe    method    to    eliminate    all detectable   seeding   activity   of misfolded   infectious   proteins, and      is      safe      for      skin      and mucosal contact.
Dodge: Exclusive Distribution for Funeral Service From      its      founding      in      1893,      Dodge      has      consistently developed   and   delivered   innovative   products   that   serve   the needs   of   the   funeral   industry.      Since   its   early   years   with   the establishment   of   schools   to   teach   the   science   of   embalming, to     the     more     current     introduction     of     formaldehyde-free chemicals,    Dodge    has    led    the    way.    Today,    Dodge,    a    fourth generation     family     business,     is     the     largest     provider     of embalming    chemicals    and    supplies    with    subsidiaries    and distributors    located    throughout    the    world.    Briotech    Inc.    is honored    to    partner    with    this    industry    leader    for    exclusive distribution   of   BRIO      HOCL   PrP   Formula TM    into   the   funeral service industry.
BRIO      HOCL   PrP   Formula TM    is   available   through   the   Dodge Company, or its distributors, in the following countries:  
Please contact your Dodge Sales Representative at their customer service line at 800.443.6343 or email them at:  custserv@dodgeco.com 
SWEDEN UK IRELAND HOLLAND FRANCE GERMANY CZECHOSLOVAKIA BELGIUM POLAND HUNGARY ROMANIA
RUSSIA JAPAN SINGAPORE PHILIPPINES CAMBODIA VIETNAM AUSTRALIA GHANA NIGERIA UGANDA
USA CANADA MEXICO EL SALVADOR COLUMBIA JAMAICA VIRGIN ISLANDS SPAIN PORTUGAL ITALY
BRIOTECH, ITS LOGOS, LANGUAGE, AND IMAGES ARE TRADEMARKS AND/OR THE COPYRIGHT PROPERTY OF BRIOTECH, INC. AND/OR ITS AFFILIATES. © 2013-2018
B R I O T E C H ,  I N C . Woodinville, WA 98072, USA b r i o t e c h u s a .c o m
September 29th, 2016 11:02 AM PDT
NIH   Scientists   and   collaborators   report   that   Briotech   Inc.’s proprietary    HOC l     formulation    rapidly    inactivates    resistant infectious   proteins,   known   as   prions,   that   cause   Mad   Cow, Chronic    Wasting,    and    Creutzfeldt–Jakob    Disease,    and    are now     implicated     in     Alzheimer’s     and     other     chronic     brain diseases WOODINVILLE,   Wash.   (September   29,   2016)   Briotech   Inc. today   announced   that   a   study   published   in   the   current   issue of   PLOS   Pathogens       proves   that   Briotech’s   unique   formulation of     pure     hypochlorous     acid     (HOC l )     inactivates     infectious proteins,   known   as   prions,   that   cause   chronic   brain   diseases in humans and animals.  Investigators    at    the    US    National    Institute    of    Allergy    and Infectious    Diseases    (NIAID)    Rocky    Mountain    Laboratories, made   the   discovery   in   collaboration   with   researchers   at   the University      of      Washington      (UW)      Bothell,      UW      Seattle,            the    University    of    Verona    (Italy),    and    Briotech    Inc.    Their findings       demonstrate       that       Briotech’s       patent-pending solution   (BrioHOC l TM )   quickly   and   safely   destroys   prions,   the most resistant infectious agents known to medical science. HOC l     is    made    naturally    in    human    white    blood    cells    as    a                key   part   of   the   body’s   internal   defense   system.   It   works   as the    first    line    of    defense    at    wound    sites    to    fight    infection. Briotech’s    proprietary    Electro-Chemical    Activation    (ECA) technology   enables   large-scale   production   of   this   powerful natural    compound    for    use    in    consumer    and    professional healthcare settings. “We’ve    been    able    to    synthesize    the    same    pure    substance          that   the   body   creates   to   defend   itself   as   a   new   weapon   in   the fight   against   infectious   disease,   and   it’s   a   game   changer   for human   health,”   said   Dan   Terry,   founder,   and   CEO   of   Briotech. “With   broad   adoption   of   BrioHOC l TM ,   we   can   help   stop   the spread   of   many   infectious   diseases,   even   those   caused   by   the most    highly    resistant    agents    ever    discovered prions and use   the   product   to   save   lives   and   improve   the   health   of   entire communities    around    the    world.    We’re    excited    to    have    this research   published   in   PLOS   Pathogens ,   and   look   forward   to our   continued   collaboration   with   the   NIH   on   the   effects   of BrioHOC l TM    on   emerging   infectious   pathogens   that   threaten global health and safety.” DESTROYING PRIONS Prions    are    abnormal,    misfolded    body    proteins    that    go    out                of     control     and     begin     to     multiply     themselves,     spreading throughout   the   body   and   invading   the   brain.      Prions   are   most commonly     transmitted     orally,     but     can     also     contaminate medical   and   surgical   instruments,   transplanted   tissues,   and equipment   used   in   food   processing.         A   new,   fast,   convenient and       safe       method       for       decontamination       of       medical instruments,   surfaces,   and   tissues by   simple   immersion   in an    aqueous    solution    of    Briotech’s    pure    BrioHOC l TM can overcome     a     critically     important     deficiency     in     infection control   today.   It   can   mitigate   risks,   and   limit   liabilities   related to healthcare procedures and hospital acquired diseases. Prion   diseases   are   most   widely   known   as   the   cause   of   Mad Cow    Disease    (BSE).    Prions    also    cause    Creutzfeldt-Jakob Disease    (CJD)    in    humans,    a    fatal    dementia    with    a    long incubation   period.   Recently,   research   has   shown   that   most other   chronic   degenerative   diseases   that   lead   to   dementia, including       Alzheimer’s,       result       from       prions.       Currently untreatable,   and   inevitably   fatal,   controversy   swirls   around their     possible     transmissibility     as     referenced     in     Nature   / / r - alzheimers ) Prions     are     uniquely     resistant     to     the     disinfection     and sterilization     procedures     in     common     use     in     healthcare practice   today.   Extreme   measures   are   needed.   Current   prion decontamination      protocols      are      hazardous      to      people, damaging     to     instruments     and     surfaces,     and     therefore impractical   for   transmission   control.   “Briotech   has   developed an   enabling   technology,   one   that   offers   for   the   first   time   a practical    and    safe    way    of    destroying    infectious    prions,    the disease    agents    at    the    very    top    of    the    food    chain    when    it comes     to     resistance     to     disinfection     measures,”     said     Jeff Williams,    PhD,    BVSc,    Chief    Scientific    Officer    at    Briotech.      “We   believe   we’ve   just   exposed   the   tip   of   the   iceberg   when        it   comes   to   revealing   the   full   potential   of   the   pure   HOC l    in controlling     and     preventing     many     transmissible     diseases. That’s      so      important      today      when      rampant      antibiotic resistance       is       challenging       established       approaches       to infectious     disease     management     all     over     the     world.     The discovery     reported     in     PLOS     Pathogens      has     opened     new avenues    for    researchers    to    explore    in    understanding    the relationship     between     the     HOC l      made     in     the     brain,     its possible    involvement    in    prion    inactivation    there,    and    the disease    processes    that    lead    to    dementia.    Understanding those   processes   is   one   of   the   most   urgent   priorities   facing biomedical science at this time.” HOW IT WORKS BrioHOC l TM    is   easy   to   handle,   safe   for   both   users   and   treated surfaces   and   is   environmentally   safe.   Pure   HOC l ,      used   in   the PLOS    Pathogens     report,    is    reliably    stable    in    its    formulation and   powerfully   effective   against   a   wide   range   of   conventional microbial   disease   agents.   The   solution   can   be   applied   directly to   skin   and   mucous   membranes,   hard   surfaces,   instruments, or safely aerosolized to decontaminate entire rooms. Briotech      manufactures      BrioHOC l TM       in      fully-automated production   platforms   inside   20’   shipping   containers,   enabling production    and    distribution    of    a    consistent    and    pure    form              of HOC l  virtually anywhere in the world. ABOUT BRIOTECH INCORPORATED Based    in    Woodinville,    WA,    the    company    was    founded    in 2013    to    commercialize    the    production    of    pure    HOC l ,    a powerful,     safe,     naturally     occurring     substance,     effective against   the   whole   range   of   infectious   disease   pathogens   of humans     and     animals,     and     to     make     it     readily     available throughout        the        world.        Briotech’s        introduction        of transportable,   self-contained   manufacturing   systems   makes high    volume    production    of    consistent    and    reliable    HOC l   solutions    possible    for    the    first    time    ever.    Its    proprietary electrolysis   technology   creates   unique   formulations   of   stable HOC l    for   a   wide   range   of   applications   in   consumer,   medical, agricultural     and     industrial     settings.     More     information     is available at briotechusa.com . ABOUT THE RESEARCH STUDY The   research   study   titled   “Inactivation   of   Prions   and   Amyloid seeds   with   Hypochlorous   Acid”   appears   in   the   current   issue of PLOS Pathogens  here: los.org/10.1371/journal.ppat.1005914 BrioHOC l TM treatment    led    to        a    high    level    of    inactivation after   short   exposure   times   for   transmissible   prions   of   CJD, BSE,   and   CWD,   but   also   for   self-replicating   proteins   found   in Alzheimer’s,   Parkinson’s   and   other   dementias.   Infectivity   of BrioHOC l TM treated   scrapie   prions   in   mice   was   also   highly significantly reduced.
P R E S S  R E L E A S E
B R I O H O C L P r P F O R M U L A TM
The breakthrough needed to overcome a critically important deficiency in infection control. A new, fast, convenient and safe method for decontamination of medical instruments, surfaces, and tissues by simple immersion in an aqueous solution. BRIO HOCL PrP Formula TM  is a proven anti-prion reagent to combat misfolded infectious proteins, and the recommended proprietary disinfection solution to combat all misfolded infectious proteins. This patent pending product is available  for research use.